Hurthle cell cancer

DEFINITION

Hurthle (HEERT-luh) cell cancer is a rare cancer that affects the thyroid gland.

The thyroid is a butterfly-shaped gland in the base of your neck. It secretes hormones that are essential for regulating your body’s metabolism.

Hurthle cell cancer is also called Hurthle cell carcinoma or oxyphilic cell carcinoma. Hurthle cell cancer is one of several types of cancers that affect the thyroid.

Hurthle cell cancer can be more aggressive than other types of thyroid cancer. Surgery to remove the thyroid gland is the most common treatment.

CAUSES

It’s not clear what causes Hurthle cell cancer.

Doctors know that cancer begins when a cell develops errors in its DNA — the genetic material that contains instructions for biochemical processes in your body. When DNA is altered or damaged, these genes may not function properly, causing cells to grow out of control and eventually form a mass (tumor) of cancerous (malignant) cells.

SYMPTOMS

Signs and symptoms of Hurthle cell cancer may include:

  • A fast-growing lump in your neck, just below your Adam’s apple
  • Pain in your neck or throat
  • Hoarseness or other changes in your voice
  • Shortness of breath
  • Swallowing difficulty



These signs and symptoms don’t necessarily mean you have Hurthle cell cancer. They may be indications of other medical conditions — such as inflammation of the thyroid gland or a noncancerous enlargement of the thyroid (goiter).

When to see a doctor

Make an appointment with your doctor if you have any signs or symptoms that worry you.