Diseases

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DEFINITION Coarctation (ko-ahrk-TAY-shun) of the aorta — or aortic coarctation — is a narrowing of the aorta, the large blood vessel that branches off your heart and delivers oxygen-rich blood to your body. When this occurs, your heart must pump…

DEFINITION Cold urticaria (ur-tih-KAR-e-uh) is a skin reaction to cold. Skin that has been in contact with cold develops reddish, itchy welts (hives). 
   
 The severity of cold urticaria symptoms varies widely. Some people have minor reactions to…

DEFINITION Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the blood cells. The term “chronic” in chronic myelogenous leukemia indicates that this cancer tends to progress more slowly than acute forms of leukemia. The term “myelogenous” (my-uh-LOHJ-uh-nus)…

DEFINITION Chronic granulomatous disease (CGD) is an inherited (genetic) immune system disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn’t work properly. As a result, the phagocytes can’t protect your…

DEFINITION Clubfoot describes a range of foot abnormalities usually present at birth (congenital) in which your baby’s foot is twisted out of shape or position. In clubfoot, the tissues connecting the muscles to the bone (tendons) are shorter than usual.…

DEFINITION Churg-Strauss syndrome — also known as eosinophilic granulomatosis (gran-u-loe-muh-TOE-sis) with polyangiitis (pol-e-an-jee-I-tis) — is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to vital organs and tissues, sometimes permanently damaging them. 
   
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DEFINITION Chronic lymphocytic leukemia (CLL) is a type of cancer of the blood and bone marrow – the spongy tissue inside bones where blood cells are made. 
   
 The term “chronic” in chronic lymphocytic leukemia comes from the…

DEFINITION Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcohol abuse. The liver carries out several necessary functions, including detoxifying harmful substances in…

DEFINITION Chronic traumatic encephalopathy (CTE) results from blows to the head over a period of time that cause concussion (mild traumatic brain injury). These injuries lead to difficulties with thinking (cognition), emotions and behaviors that do not become noticeable until…

DEFINITION Charcot (shahr-KOH)-Marie-Tooth disease is a group of hereditary disorders that damage the nerves in your arms and legs (peripheral nerves). Charcot-Marie-Tooth is also known as hereditary motor and sensory neuropathy. 
   
 The main signs and symptoms of…

DEFINITION Chemo brain is a common term used by cancer survivors to describe thinking and memory problems that can occur after cancer treatment. Chemo brain can also be called chemo fog, chemotherapy-related cognitive impairment or cognitive dysfunction. Though chemo brain…