{"id":812,"date":"2022-05-24T16:50:18","date_gmt":"2022-05-24T12:50:18","guid":{"rendered":"https:\/\/gh.ge\/en\/disease\/wegeners-granulomatosis\/"},"modified":"2022-05-24T16:50:18","modified_gmt":"2022-05-24T12:50:18","slug":"wegeners-granulomatosis","status":"publish","type":"disease","link":"https:\/\/gh.ge\/en\/disease\/wegeners-granulomatosis\/","title":{"rendered":"Wegener’s granulomatosis"},"content":{"rendered":"

DEFINITION<\/h2>\n

Wegener’s granulomatosis (VEG-eh-nerz gran-u-loe-muh-TOE-sis) is an uncommon disorder that causes inflammation of your blood vessels. This inflammation restricts blood flow to various organs. <\/p>\n

Wegener’s granulomatosis, which is also called granulomatosis with polyangiitis (GPA), often affects your kidneys, lungs and upper respiratory tract. The restricted blood flow to these organs can damage them. Wegener’s can affect other organs, but this isn’t as common, and generally isn’t as serious. <\/p>\n

Wegener’s granulomatosis also produces a type of inflammatory tissue known as a granuloma that’s found around the blood vessels. Granulomas can destroy normal tissue. There is no known cause for Wegener’s granulomatosis. <\/p>\n

Early diagnosis and treatment of Wegener’s granulomatosis may lead to a full recovery. Without treatment, Wegener’s granulomatosis can be fatal, most commonly from kidney failure.<\/p>\n

CAUSES<\/h2>\n

The cause of Wegener’s granulomatosis is unknown. It appears to develop after an initial inflammation-causing event triggers an abnormal reaction from your immune system. The combination of these events can lead to inflamed, constricted blood vessels and harmful inflammatory tissue masses (granulomas). The triggering event may be an infection, but no specific infection has been identified as the cause.<\/p>\n

SYMPTOMS<\/h2>\n

Signs and symptoms of Wegener’s granulomatosis may develop suddenly or over several months. <\/p>\n

The first Wegener’s granulomatosis symptoms usually involve areas of your respiratory tract, such as your sinuses, throat or lungs. However, the condition often worsens rapidly, affecting blood vessels and the organs they supply, such as the kidneys. Signs and symptoms may include: <\/p>\n

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